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Learn more about PEPR Centers of Excellence, leaders, and studies

The PEPR team at Northwestern University enhancing the understanding of the effects of asthma and atopic dermatitis (eczema) on children’s well-being. Investigators are using PROMIS tools to assess fatiguepainmobility, physical function, depressive symptomsanxietystress, and peer relationships. The center is also developing a new patient-reported outcome measure for itch. The team is collecting PRO measures in multiple settings (general population, doctor’s office, hospital) from ethnically and socioeconomically diverse samples of patients recruited from three ongoing pediatric asthma clinical trials and an Eczema Center.

 

Northwestern University’s PEPR Center is partnering with the following performance sites: Boston Children’s Hospital, Washington University and University of Illinois at Chicago.

Medical College of Wisconsin (MCW) is helping researchers to better understand how sickle cell disease, asthma, and type 1 diabetes affect children’s quality of life. Researchers are evaluating PROMIS tools that measure pain, physical activity, stress, strength, and family relationships. The project is also focused on understanding how environmental factors (including socioeconomic factors) at the individual and community levels affect children’s health. The research is being conducted in emergency department and health clinic settings.

Medical College of Wisconsin is partnering with The University of Wisconsin, Madison to complete this work

The PEPR team at Children's Hospital of Philadelphia (CHOP) is leveraging existing clinical studies to understand the experiences of children with Crohn’s disease and chronic kidney disease and cancer survivors. The investigators hope to learn how these diseases influence children’s pain, fatigue, stress, and sleep using PROMIS measures. The CHOP center also administers an Infrastructure and Opportunities Fund for the entire Consortium to support resources that provide additional assistance or technical expertise for projects undertaken by PEPR investigators.​

CHOP is partnering with performance sites at St. Jude Children's Research Hospital and the University of North Carolina.

The Duke University School of Medicine PEPR Center is focused on understanding how living with juvenile idiopathic arthritis, lupus, cancer, or inflammatory bowel disease affects children’s well-being. Researchers will leverage several pediatric data collection networks to test PROMIS tools that assess pain, fatigue, physical function, stress, anxiety, depressive symptoms, sense of meaning and purpose, quality of family life and peer relationships, in children with these chronic conditions.

Duke is partnering with The University of North Carolina to complete this work. 

PEPR Consortium Structure
pepr steering committee

IOF Management Core

children's

Hospital of

Philadelphia

duke

university

medical

College of

Wisconsin 

Data repository

northwestern

University

Each PEPR study will contribute a limited dataset, comprised of demographics and PRO data, to a data repository. The data will be housed on Harvard Dataverse and will be publicly available. 

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